5 Key Takeaways

• 1

  Keratoconus is often progressive and frequently diagnosed late, lacking universally accepted screening strategies for at-risk individuals.

• 2

  A systematic review highlights the significant role of hormonal fluctuations in the onset and progression of keratoconus.

• 3

  The review analyzed 26 studies over six decades, linking keratoconus to hormonal changes, particularly during pregnancy.

• 4

  Elevated DHEAS levels were consistently reported in keratoconus patients, indicating a systemic component to the disease.

• 5

  The findings suggest integrating hormonal history into keratoconus risk assessments and developing targeted screening pathways.