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The Ophthalmologist / Issues / 2026 / May / Phase 3 Win for TED Therapy
News Latest Research & Innovations

Phase 3 Win for TED Therapy

Amgen’s subcutaneous TEPEZZA meets phase 3 endpoints in thyroid eye disease

5/8/2026 2 min read

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  • Full Article
  • Summary
  • Takeaways
  • Report
  • Poll
  • Top Institutions
Top Institutions in Endocrinology

The ranking combines internal corpus citation frequency with web search results due to limited internal data for this topic.

  • #1

    University of Michigan – Michigan Medicine, W.K. Kellogg Eye Center

    Ann Arbor, Michigan

    Michigan led the bench-to-bedside work identifying IGF-1R in TED pathogenesis and co-led the pivotal Phase 2 and Phase 3 studies that established teprotumumab’s efficacy.

    Key Differentiators

    • Endocrinology
    • Ophthalmology
  • #2

    Cedars-Sinai Medical Center

    Los Angeles, California

    Cedars-Sinai’s Raymond S. Douglas was lead author of the NEJM Phase 3 OPTIC trial and continues to drive prospective studies in TED.

    Key Differentiators

    • Endocrinology
    • Ophthalmology
  • #3

    Dana-Farber Cancer Institute

    Boston, Massachusetts

    Dana-Farber's involvement in the Phase 3 study highlights its commitment to advancing treatment for TED.

    Key Differentiators

    • Oncology
    • Endocrinology
  • #4

    Byers Eye Institute, Stanford University School of Medicine

    Stanford, California

    The institute is recognized for its contributions to ophthalmology and its involvement in TED research.

    Key Differentiators

    • Ophthalmology
    • Endocrinology
  • #5

    Vall d’Hebron Institute of Oncology

    Barcelona, Spain

    The institute is noted for its research in oncology and its contributions to TED therapy.

    Key Differentiators

    • Oncology
    • Endocrinology

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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