5 Key Takeaways

• 1

  A retrospective study followed 120 treatment-naïve eyes with neovascular age-related macular degeneration (nAMD) for at least 6 years after anti-VEGF treatment.

• 2

  Overall, 71% of eyes lost fewer than 15 ETDRS letters, with no significant difference in visual retention among conventional nAMD, polypoidal choroidal vasculopathy, and retinal angiomatous proliferat

• 3

  Under the drusen-pachychoroid classification, 82% of pachychoroid-type eyes maintained vision, compared with 38% of drusen-type eyes.

• 4

  At 6 years, complete retinal pigment epithelial and outer retinal atrophy prevalence was highest in the drusen group at 61.5%, versus 27.2% in the pachychoroid group.

• 5

  The findings are exploratory because the study was retrospective, single-center, and included small subgroups; the authors called for prospective studies to establish causality.