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The Ophthalmologist / Issues / 2026 / September / New Data for Bioerodible DURAVYU in Wet AMD
Retina Research & Innovations Interview

New Data for Bioerodible DURAVYU in Wet AMD

Tarek S. Hassan provides perspective on the Phase 3 LUGANO topline results and the path forward for DURAVYU in wet age-related macular degeneration (AMD)

9/17/2026 3 min read

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5 Key Takeaways
  • 1

    The LUGANO trial evaluated DURAVYU (EYP-1901) against aflibercept in wet AMD but did not meet the primary endpoint for visual acuity.

  • 2

    Nine DURAVYU patients experienced ≥15-letter vision loss from causes unrelated to neovascular AMD, impacting trial results.

  • 3

    DURAVYU demonstrated strong anatomic control and reduced treatment burden, with 76% of patients remaining supplement-free at Week 32.

  • 4

    The trial showed a 42% reduction in treatment burden compared to aflibercept, indicating fewer required injections.

  • 5

    The next Phase 3 trial, LUCIA, is expected to provide further data, with results anticipated in Q4 2026.

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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