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The Ophthalmologist / Issues / 2026 / June / The Fellow Eye Is Never Just a Bystander
Health Economics and Policy Opinions Voices in the Community

The Fellow Eye Is Never Just a Bystander

What does the “fellow eye effect” reveal about ophthalmology’s pre-existing notions of unilateral eye disease?

By Hashem Abu Serhan 6/29/2026 3 min read

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4 Topic Commentaries

The Fellow Eye Is Never Just a Bystander

The Fellow Eye Is Never Just a Bystander

  • Kelly Donovan
    Kelly Donovan, MD, PhD

    Ophthalmology

    •

    Duke Eye Center, Duke University Medical Center

    In short, the extensive analyses used in this study showed an underwhelming correlation between fellow eyes.

    Source
  • Tiarnán D. L. Keenan
    Tiarnán D. L. Keenan, BM BCh, PhD

    Ophthalmology

    •

    National Eye Institute, National Institutes of Health

    Meaning Results suggest that the GA enlargement rate in 1 eye often does not consistently predict the enlargement rate in the fellow eye; this assumption should be used cautiously in designing clinical trials or inferring treatment effects.

    Source
  • Devinder S. Chauhan
    Devinder S. Chauhan, FRCOphth, MD

    Ophthalmology

    •

    Moorfields Eye Hospital, London

    A crucial guide to the level of risk for a fellow eye is the presence or absence of a posterior vitreous detachment.

    Source
  • Kazuyuki Kumagai
    Kazuyuki Kumagai, MD

    Ophthalmology

    •

    Shinjo Ophthalmologic Institute

    Curve-fit analysis showed that the estimated risk of MH in the fellow eye was 12.0% at 5 years and 16.9% at 10 years.

    Source

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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